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Palexia IR Tablets 50mg – Tapentadol Hydrochloride
Active Ingredient: Tapentadol 50 mg (as tapentadol hydrochloride)
Formulation: Immediate-Release, film-coated oral tablet
Palexia IR 50 mg delivers rapid-onset relief for severe, acute pain when alternative analgesics are inadequate. Each tablet contains tapentadol, an opioid agonist with dual mechanisms of action – μ-opioid receptor agonism and noradrenaline re-uptake inhibition – providing effective pain control with a favourable gastrointestinal tolerability profile.


Strength: 50mg tapentadol per tablet

Indication: Short-term management of severe acute pain responsive to opioid therapy

Onset: Rapid absorption; peak plasma levels typically within 1 hour

Dosing: Individualised – usually 50–100 mg every 4–6 hours as required, not to exceed 600 mg in 24 hours

Schedule: Schedule 8 (Controlled Drug) – Prescription Only Medicine


Pack Sizes: Commonly supplied in blister packs of 20 & 60 tablets (check availability)

Excipients: Includes lactose, povidone, and magnesium stearate (full list in CMI/PI)

Storage: Store below 25 °C in a dry place; keep out of reach of children

Manufacturer: Grünenthal GmbH / Seqirus (Australia) Pty Ltd

Clinical Considerations: Palexia IR should be reserved for patients where non-opioid and step-two opioid analgesics are insufficient. Monitor for opioid-related adverse effects and signs of misuse. Contra-indicated in severe respiratory depression, acute asthma, or paralytic ileus.
Prescription Only Medicine – Authorised prescriber required.Always read the Product Information before prescribing. This web page is provided for professional reference only and is not a substitute for medical advice. Use strictly as directed.
Order from Medshop – registered healthcare practitioners can source Palexia IR 50 mg quickly and securely through our pharmaceutical supply channel.

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Brand:Seqirus AustraliaSKU:PHA17038Tags:Controlled Pharma, Pharmaceutical, Pharmacy